MDAT

MDAT (Multiple Domain Alignment Tool) is a program to align domain arrangements with each other. It provides an alignment output similar to normal multiple sequence alignments but with protein domains as alignable units.

The current version can be found here: MDATv1.2.tar.gz

Installation

 tar xfz MDATv1.2.tar.gz
 cd MDAT
 cmake ..
 make

Usage

To run the program call:

./mdat -s <fasta file> -d <pfam annotation> -a <output file>

Future

We plan to reimplement this program so it can be incorporated into the new DomainWorld framework. That will allow to use the new Domain Similarity Matrix.

Citation

If you used MDAT in your project please cite our publication:

Kemena C, Bitard-Feildel T, Bornberg-Bauer E, MDAT - Aligning multiple domain arrangements, BMC Bioinformatics. 2015;16(1):19. doi:10.1186/s12859-014-0442-7

https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-014-0442-7